Active Pharmaceutical Ingredient

Imipramine

Also known as: Tofranil / Pryleugan

CAS: 50-49-7 Tricyclic Antidepressant (TCA) IP / BP / EP / USP Bulk Supply Available
Imipramine API Manufacturer India | Mediocon Inc
Imipramine — Pharmaceutical Grade API

Product Overview

CAS No: 50-49-7  |  MF: C₁₉H₂₄N₂  |  MW: 280.41 g/mol

Imipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine and serotonin. It is used in the treatment of depression, panic disorder, and enuresis. Mediocon Inc supplies pharmaceutical-grade Imipramine HCl API meeting IP/BP/EP/USP standards.

Key Features

  • First tricyclic antidepressant (TCA)
  • IP/BP/EP/USP compliant quality
  • Inhibits NE and 5-HT reuptake
  • Suitable for tablet and solution formulations

Applications

  • Major depressive disorder
  • Panic disorder and agoraphobia
  • Childhood nocturnal enuresis
  • Neuropathic pain (off-label)

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameImipramine
Also Known AsTofranil / Pryleugan
CAS Number50-49-7
Molecular FormulaC₁₉H₂₄N₂
Molecular Weight280.41 g/mol
CategoryTricyclic Antidepressant (TCA)
AppearanceWhite to Off-white Crystalline Powder
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
Assay99.0% – 101.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
pH4.5 – 5.5 (HCl salt solution)
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing25 kg HDPE drums / as per requirement
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