Also known as: DB289; Pafuramidine maleate
Pafuramidine (DB289) is an orally bioavailable diamidine prodrug used in the treatment of African sleeping sickness (Trypanosoma brucei gambiense) and Pneumocystis pneumonia. Mediocon Inc manufactures this API at its GMP-certified facility in Aurangabad, Maharashtra, India, ensuring high purity and compliance with international pharmacopoeial standards.
| Parameter | Specification |
|---|---|
| CAS Number | 58-38-0 |
| Molecular Formula | C21H27N7O2·2HCl |
| Molecular Weight | 480.40 g/mol |
| Grade | IP / BP / USP |
| Category | Antiprotozoal / Antimicrobial Agent |
| Appearance | Pale yellow to yellow crystalline powder |
| Solubility | Freely soluble in water, sparingly soluble in ethanol, practically insoluble in ether |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PAF/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |