Active Pharmaceutical Ingredient

Pegaptanib Octasodium — CAS 222716-86-1

Also known as: Macugen; EYE001; NX1838

GMP Certified IP / BP / EP / USP VEGF Antagonist / Anti-angiogenic (RNA Aptamer) Aurangabad, India
Pegaptanib Octasodium API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pegaptanib Octasodium IP / BP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 222716-86-1

Product Overview

Pegaptanib Octasodium is a high-purity Active Pharmaceutical Ingredient (API) classified as a VEGF Antagonist / Anti-angiogenic (RNA Aptamer). Manufactured by Mediocon Inc in Aurangabad, Maharashtra, India at a GMP-certified facility, it is supplied in bulk for pharmaceutical formulations worldwide. CAS No: 222716-86-1.

Therapeutic Applications
  • Neovascular (wet) age-related macular degeneration (AMD)
  • Inhibition of VEGF165-mediated ocular angiogenesis
  • Macular oedema associated with retinal vein occlusion
  • Diabetic macular oedema (investigational)
  • Intraocular anti-VEGF therapy

Technical Specifications

ParameterSpecification
CAS Number222716-86-1
Molecular FormulaPegylated RNA Aptamer (Octasodium salt)
Molecular Weight~50,000 g/mol (PEGylated)
GradeIP / BP / EP / USP
CategoryVEGF Antagonist / Anti-angiogenic (RNA Aptamer)
AppearanceWhite to off-white lyophilized powder
SolubilitySoluble in water and phosphate-buffered saline
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Mfg DateMAR 2025
Exp DateFEB 2030
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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