Active Pharmaceutical Ingredient

Pramoxine Hydrochloride — CAS 637-58-1

Also known as: Pramocaine Hydrochloride; Tronothane Hydrochloride

GMP Certified IP / BP / USP Local Anesthetic Aurangabad, India
Pramoxine Hydrochloride API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pramoxine Hydrochloride IP / BP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 637-58-1

Product Overview

Pramoxine Hydrochloride is a topical local anesthetic agent manufactured by Mediocon Inc at its GMP-certified facility in Aurangabad, Maharashtra, India. It is used in creams, lotions, and suppositories for relief of pain and itching associated with skin conditions. CAS No: 637-58-1.

Therapeutic Applications
  • Topical relief of minor skin irritations, itching, and pain
  • Used in hemorrhoidal preparations for anorectal discomfort
  • Component of anti-itch creams and lotions
  • First-aid formulations for minor burns and insect bites

Technical Specifications

ParameterSpecification
CAS Number637-58-1
Molecular FormulaC13H30N2O2·HCl
Molecular Weight354.86 g/mol
GradeIP / BP / USP
CategoryLocal Anesthetic
AppearanceWhite to off-white crystalline powder
SolubilityFreely soluble in water, soluble in ethanol. Practically insoluble in chloroform.
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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