Active Pharmaceutical Ingredient

Raltitrexed — CAS 112887-68-0

Also known as: Tomudex; ZD1694; ICI D1694

GMP Certified IP / BP / EP / USP Thymidylate Synthase Inhibitor / Antineoplastic Aurangabad, India
Raltitrexed API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Raltitrexed IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 112887-68-0

Product Overview

Raltitrexed is a specific thymidylate synthase (TS) inhibitor used in the treatment of advanced colorectal cancer. It is a folate analogue that inhibits DNA synthesis. Mediocon Inc manufactures GMP-compliant Raltitrexed at its Aurangabad facility to international pharmacopoeial standards.

Therapeutic Applications
  • Colorectal cancer treatment
  • Thymidylate synthase inhibitor
  • Antineoplastic / antifolate chemotherapy
  • Palliative treatment of advanced colorectal carcinoma

Technical Specifications

ParameterSpecification
CAS Number112887-68-0
Molecular FormulaC₂₁H₂₂N₄O₆S
Molecular Weight458.49 g/mol
GradeIP / BP / EP / USP
CategoryThymidylate Synthase Inhibitor / Antineoplastic
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoRLT/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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