Active Pharmaceutical Ingredient

Ruxolitinib — CAS 941678-49-5

Also known as: Jakafi; Jakavi; INCB018424

GMP Certified IP / BP / EP / USP JAK1/JAK2 Inhibitor / Antineoplastic Agent Aurangabad, India
Ruxolitinib API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Ruxolitinib IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 941678-49-5

Product Overview

Ruxolitinib is a high-purity Active Pharmaceutical Ingredient (API) classified under JAK1/JAK2 Inhibitor / Antineoplastic Agent. Mediocon Inc manufactures GMP-compliant Ruxolitinib at its state-of-the-art facility in Aurangabad, Maharashtra, India, supplying pharmaceutical companies worldwide with consistent quality and full regulatory documentation.

Therapeutic Applications
  • Myelofibrosis (MF) treatment
  • Polycythaemia vera
  • Acute graft-versus-host disease (aGvHD)
  • Atopic dermatitis (topical formulation)

Technical Specifications

ParameterSpecification
CAS Number941678-49-5
Molecular FormulaC₁₇H₁₈N₆
Molecular Weight306.37 g/mol
GradeIP / BP / EP / USP
CategoryJAK1/JAK2 Inhibitor / Antineoplastic Agent
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoRUX/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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