Active Pharmaceutical Ingredient

Sagopilone

Also known as: ZK-EPO; Epothilone Z

CAS: 92206-54-7 Antineoplastic / Epothilone IP / BP / EP / USP GMP Certified Aurangabad, Maharashtra, India
Sagopilone API — Mediocon Inc, Aurangabad Maharashtra India
Sagopilone — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 92206-54-7  |  MF: C₂₆H₃₅NO₄S  |  MW: 461.63 g/mol

Sagopilone is a fully synthetic epothilone B analogue with potent microtubule-stabilising activity. Mediocon Inc supplies pharmaceutical-grade Sagopilone conforming to IP / BP / EP / USP specifications from our GMP-certified facility in Aurangabad, Maharashtra, India.

Sagopilone demonstrates superior blood-brain barrier penetration compared to other epothilones, making it particularly relevant in CNS oncology research. It is active against taxane-resistant cancer cell lines.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Oncology drug formulations
  • Brain cancer research
  • Taxane-resistant tumour therapy
  • Preclinical cancer research

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameSagopilone
Also Known AsZK-EPO; Epothilone Z
CAS Number92206-54-7
Molecular FormulaC₂₆H₃₅NO₄S
Molecular Weight461.63 g/mol
CategoryAntineoplastic / Epothilone
AppearanceWhite to off-white powder
SolubilitySparingly soluble in water; soluble in DMSO and ethanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Mfg DateMAR 2025
Exp DateFEB 2030
Packing25 kg HDPE drums / as per requirement
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