Active Pharmaceutical Ingredient

Tolnaftate

Also known as: Tinactin; Aftate; N-(1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethyl) naphthalene-1-thioamide

CAS: 2398-96-1Topical Antifungal / APIIP / BP / EP / USPGMP CertifiedAurangabad, Maharashtra, India
Tolnaftate API — Mediocon Inc
Tolnaftate — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 2398-96-1  |  MF: C₁₈H₁₇NOS  |  MW: 307.40 g/mol

Tolnaftate is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Tolnaftate is a synthetic thiocarbamate antifungal agent that inhibits the enzyme squalene epoxidase, disrupting ergosterol biosynthesis in fungal cell membranes. It is widely used for the topical treatment of tinea infections.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Tinea pedis (athlete's foot)
  • Tinea cruris (jock itch)
  • Tinea corporis (ringworm)
  • Onychomycosis adjunct therapy

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTolnaftate
Also Known AsTinactin; Aftate; N-(1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethyl) naphthalene-1-thioamide
CAS Number2398-96-1
Molecular FormulaC₁₈H₁₇NOS
Molecular Weight307.40 g/mol
CategoryTopical Antifungal Agent / Active Pharmaceutical Ingredient
AppearanceWhite to creamy white powder
SolubilityPractically insoluble in water; soluble in acetone and ethanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TNA/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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