Active Pharmaceutical Ingredient

Trilostane

Also known as: Modrastane; WIN 24540

CAS: 13647-35-3Steroid Inhibitor APIIP / BP / EP / USPGMP CertifiedAurangabad, Maharashtra, India
Trilostane API — Mediocon Inc
Trilostane — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 13647-35-3  |  MF: C₂₀H₂₇NO₂  |  MW: 329.43 g/mol

Trilostane is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Trilostane is a synthetic steroid that reversibly inhibits 3β-hydroxysteroid dehydrogenase, thereby blocking adrenal cortex steroid synthesis. It is used in veterinary medicine for canine hyperadrenocorticism and has been investigated for Cushing's syndrome.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Canine Cushing's disease (hyperadrenocorticism)
  • Adrenocortical excess disorders
  • Hormone-sensitive tumour research
  • Adrenal steroidogenesis studies

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTrilostane
Also Known AsModrastane; WIN 24540
CAS Number13647-35-3
Molecular FormulaC₂₀H₂₇NO₂
Molecular Weight329.43 g/mol
CategoryAdrenal Steroid Biosynthesis Inhibitor
AppearanceWhite to off-white crystalline powder
SolubilityPractically insoluble in water; soluble in methanol and chloroform
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TSL/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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