Active Pharmaceutical Ingredient

Vandetanib

Also known as: ZD6474; Caprelsa

CAS: 443913-73-3Kinase Inhibitor APIIP / BP / EP / USPGMP CertifiedAurangabad, Maharashtra, India
Vandetanib API — Mediocon Inc
Vandetanib — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 443913-73-3  |  MF: C₂₂H₂₄ClFN₄O₂  |  MW: 475.90 g/mol

Vandetanib is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Vandetanib is an oral multi-kinase inhibitor targeting VEGFR, EGFR, and RET signalling pathways. It is approved for the treatment of unresectable, locally advanced, or metastatic medullary thyroid cancer and is under investigation for other malignancies.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Medullary thyroid cancer (MTC)
  • VEGFR/EGFR/RET inhibition research
  • Antineoplastic oncology therapy
  • Targeted cancer drug development

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameVandetanib
Also Known AsZD6474; Caprelsa
CAS Number443913-73-3
Molecular FormulaC₂₂H₂₄ClFN₄O₂
Molecular Weight475.90 g/mol
CategoryTyrosine Kinase Inhibitor / Antineoplastic Agent
AppearanceWhite to off-white crystalline powder
SolubilityPractically insoluble in water; sparingly soluble in methanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.VDT/24033056
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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