Active Pharmaceutical Ingredient

Promethazine

Also known as: Phenergan; Avomine

CAS: 60-87-7 First-generation Antihistamine IP / BP / EP / USP GMP Certified Aurangabad, Maharashtra, India
Promethazine API — Mediocon Inc
Promethazine — Pharmaceutical Grade API

Product Overview

CAS No: 60-87-7  |  MF: C₁₇H₂₀N₂S  |  MW: 284.42 g/mol

Promethazine is a pharmaceutical-grade active ingredient classified as a First-generation Antihistamine and Phenothiazine derivative. Mediocon Inc supplies high-purity Promethazine API conforming to IP / BP / EP / USP specifications, manufactured in our GMP-certified facility in Aurangabad, Maharashtra, India.

Promethazine competitively blocks H1 histamine receptors and also has anticholinergic, sedative, and antiemetic properties. Its broad pharmacological profile makes it suitable for allergy management, motion sickness, and as an adjunct sedative and antiemetic in clinical settings.

Key Features

  • High-purity pharmaceutical grade API
  • IP/BP/EP/USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing

Applications

  • Allergic reactions and rhinitis
  • Motion sickness and nausea
  • Sedation and pre-operative medication
  • Postoperative nausea and vomiting

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NamePromethazine
Also Known AsPhenergan; Avomine
CAS Number60-87-7
Molecular FormulaC₁₇H₂₀N₂S
Molecular Weight284.42 g/mol
CategoryFirst-generation Antihistamine — Phenothiazine
AppearanceWhite to faint yellow crystalline powder
SolubilityFreely soluble in water as hydrochloride salt
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing25 kg HDPE drums / as per requirement
💬
Mediocon AI
Hello 👋 How can I help you today?