Active Pharmaceutical Ingredient

Propofol

Also known as: Diprivan; Fresofol

CAS: 2078-54-8 Intravenous Anesthetic Agent IP / BP / EP / USP GMP Certified Aurangabad, Maharashtra, India
Propofol API — Mediocon Inc
Propofol — Pharmaceutical Grade API

Product Overview

CAS No: 2078-54-8  |  MF: C₁₂H₁₈O  |  MW: 178.27 g/mol

Propofol is a pharmaceutical-grade active ingredient classified as an Intravenous Anesthetic Agent. Mediocon Inc supplies high-purity Propofol API conforming to IP / BP / EP / USP specifications, manufactured in our GMP-certified facility in Aurangabad, Maharashtra, India.

Propofol is a short-acting phenolic intravenous anesthetic that enhances GABA-mediated chloride influx in the CNS, producing rapid sedation and anesthesia. Its rapid onset and short duration of action, with minimal accumulation, have made it the most widely used induction and maintenance anesthetic globally.

Key Features

  • High-purity pharmaceutical grade API
  • IP/BP/EP/USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing

Applications

  • General anesthesia induction and maintenance
  • ICU sedation in mechanically ventilated patients
  • Procedural sedation (endoscopy, etc.)
  • Post-operative antiemetic effect

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NamePropofol
Also Known AsDiprivan; Fresofol
CAS Number2078-54-8
Molecular FormulaC₁₂H₁₈O
Molecular Weight178.27 g/mol
CategoryIntravenous Anesthetic Agent
AppearanceColorless to pale yellow liquid
SolubilityPractically insoluble in water; formulated as oil-in-water emulsion
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing25 kg HDPE drums / as per requirement
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