Active Pharmaceutical Ingredient

Pegloticase — CAS N/A (Biologic PEGylated Uricase)

Also known as: Krystexxa; PEG-uricase

GMP Certified I.P. / B.P. / E.P. / U.S.P. Uricase Enzyme / Biologic / Anti-Gout Agent Aurangabad, India
Pegloticase API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pegloticase I.P. / B.P. / E.P. / U.S.P.  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: N/A (Biologic PEGylated Uricase)

Product Overview

Pegloticase is a high-purity Active Pharmaceutical Ingredient (API) classified as a Uricase Enzyme / Biologic / Anti-Gout Agent. Manufactured by Mediocon Inc in Aurangabad, Maharashtra, India at a GMP-certified facility, it is supplied in bulk for pharmaceutical formulations worldwide. CAS No: N/A (Biologic PEGylated Uricase).

Therapeutic Applications
  • Chronic refractory gout unresponsive to conventional therapy
  • Tophaceous gout reduction
  • Hyperuricemia management in gout
  • Uric acid lowering in gout flares
  • Biologic therapy for severe gout

Technical Specifications

ParameterSpecification
CAS NumberN/A (Biologic PEGylated Uricase)
Molecular FormulaPEGylated Uricase (Recombinant)
Molecular Weight~540 kDa
GradeI.P. / B.P. / E.P. / U.S.P.
CategoryUricase Enzyme / Biologic / Anti-Gout Agent
AppearanceWhite to off-white crystalline powder
SolubilitySlightly soluble in water; soluble in methanol
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPGL2503021
Mfg DateMAR 2025
Exp DateFEB 2030
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: I.P. / B.P. / E.P. / U.S.P. standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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