Active Pharmaceutical Ingredient

Pergolide — CAS 66104-22-1

Also known as: Permax (brand); LY-127809; Pergolide free base

GMP Certified IP / BP / EP / USP Dopamine Agonist / Antiparkinsonian Aurangabad, India
Pergolide API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pergolide IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 66104-22-1

Product Overview

Pergolide is a potent ergoline-derived dopamine receptor agonist used in the treatment of Parkinson's disease. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India. Pergolide acts on D1 and D2 dopamine receptor subtypes and was used as adjunctive therapy with levodopa/carbidopa. It is also used in veterinary medicine for the treatment of equine Pituitary Pars Intermedia Dysfunction (PPID/Cushings disease).

Therapeutic Applications
  • Parkinson's disease management as adjunct to levodopa
  • Equine Cushing's disease (PPID) — veterinary pharmaceutical use
  • Restless leg syndrome research applications
  • Hyperprolactinemia (investigational dopaminergic use)

Technical Specifications

ParameterSpecification
CAS Number66104-22-1
Molecular FormulaC₁₉H₂₆N₂S
Molecular Weight314.49 g/mol
GradeIP / BP / EP / USP
CategoryDopamine Agonist / Antiparkinsonian
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPEG/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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