Active Pharmaceutical Ingredient

Pergolide Mesylate — CAS 66104-23-2

Also known as: Permax Mesylate; LY-127809 Mesylate; Pergolide Methanesulfonate

GMP Certified IP / BP / EP / USP Dopamine Agonist / Antiparkinsonian Aurangabad, India
Pergolide Mesylate API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pergolide Mesylate IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 66104-23-2

Product Overview

Pergolide Mesylate is the methanesulfonate salt of Pergolide, the ergoline dopamine agonist. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India. The mesylate salt form provides improved pharmaceutical stability and solubility compared to the free base. Pergolide Mesylate was the commercially approved form (Permax) and remains widely used in veterinary medicine for equine PPID. It exhibits potent D1 and D2 receptor agonist activity.

Therapeutic Applications
  • Adjunctive therapy in Parkinson's disease with levodopa (human pharma)
  • Equine Pituitary Pars Intermedia Dysfunction (PPID/Cushing's) — veterinary use
  • Dopaminergic research applications
  • API supply for Pergolide mesylate tablet and oral formulations

Technical Specifications

ParameterSpecification
CAS Number66104-23-2
Molecular FormulaC₂₀H₃₀N₂O₃S₂
Molecular Weight410.59 g/mol
GradeIP / BP / EP / USP
CategoryDopamine Agonist / Antiparkinsonian
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPGM/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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