Active Pharmaceutical Ingredient

Phenprocoumon — CAS 435-97-2

Also known as: Marcoumar (brand); Marcumar (brand); 3-(1-Phenylpropyl)-4-hydroxycoumarin

GMP Certified IP / BP / EP / USP Anticoagulant / Vitamin K Antagonist Aurangabad, India
Phenprocoumon API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Phenprocoumon IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 435-97-2

Product Overview

Phenprocoumon is a long-acting oral anticoagulant of the coumarin class and Vitamin K antagonist. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India. Widely used in European countries, particularly Germany and Switzerland, Phenprocoumon inhibits vitamin K-dependent clotting factor synthesis (II, VII, IX, X) and proteins C and S. Its long half-life (~5-6 days) requires careful dosing but provides stable INR levels.

Therapeutic Applications
  • Prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism
  • Stroke prevention in atrial fibrillation
  • Thromboembolism prophylaxis after cardiac valve replacement
  • Long-term anticoagulation therapy in Europe

Technical Specifications

ParameterSpecification
CAS Number435-97-2
Molecular FormulaC₁₈H₁₆O₃
Molecular Weight280.32 g/mol
GradeIP / BP / EP / USP
CategoryAnticoagulant / Vitamin K Antagonist
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPHP/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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