Also known as: Regitine (brand); Rogitine (brand); Phentolamine Methanesulfonate
Phentolamine Mesylate is a non-selective, reversible alpha-adrenergic receptor blocker used in the management of hypertensive emergencies and pheochromocytoma. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India. It blocks both alpha-1 and alpha-2 adrenoceptors, causing vasodilation and reduction of blood pressure. It is also used intravenously to reverse local anesthesia and in the treatment of erectile dysfunction.
| Parameter | Specification |
|---|---|
| CAS Number | 65-28-1 |
| Molecular Formula | C₁⁷H₁ₙN₃O₄S |
| Molecular Weight | 377.46 g/mol |
| Grade | IP / BP / EP / USP |
| Category | Alpha-Adrenergic Blocker / Antihypertensive |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PHM/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |