Active Pharmaceutical Ingredient

Trimethadione

Also known as: Troxidone; Tridione

CAS: 127-48-0Anticonvulsant APIIP / BP / EP / USPGMP CertifiedAurangabad, Maharashtra, India
Trimethadione API — Mediocon Inc
Trimethadione — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 127-48-0  |  MF: C₆H₉NO₃  |  MW: 143.14 g/mol

Trimethadione is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Trimethadione is an oxazolidinedione anticonvulsant that was historically used in the treatment of absence (petit mal) seizures. It reduces T-type calcium currents in thalamic neurons, suppressing the oscillatory activity that generates absence seizures.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Absence seizure management (historical)
  • Anticonvulsant pharmaceutical research
  • Epilepsy drug development
  • Calcium channel pharmacology studies

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTrimethadione
Also Known AsTroxidone; Tridione
CAS Number127-48-0
Molecular FormulaC₆H₉NO₃
Molecular Weight143.14 g/mol
CategoryAnticonvulsant / Antiepileptic Agent
AppearanceWhite crystalline granules with camphor-like odour
SolubilitySoluble in water, ethanol, and chloroform
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TMDN24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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