Active Pharmaceutical Ingredient

Trimethoprim

Also known as: TMP; Proloprim; Monotrim

CAS: 738-70-5Antibacterial APIIP / BP / EP / USPGMP CertifiedAurangabad, Maharashtra, India
Trimethoprim API — Mediocon Inc
Trimethoprim — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 738-70-5  |  MF: C₁₄H₁₈N₄O₃  |  MW: 290.32 g/mol

Trimethoprim is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Trimethoprim is a synthetic antibacterial agent that selectively inhibits bacterial dihydrofolate reductase (DHFR), blocking the synthesis of tetrahydrofolic acid essential for nucleotide biosynthesis. It is often combined with sulfamethoxazole (co-trimoxazole) for broad-spectrum antibacterial therapy.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Urinary tract infections (UTI)
  • Pneumocystis pneumonia prophylaxis
  • Respiratory tract infections
  • Co-trimoxazole (TMP-SMX) formulations

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTrimethoprim
Also Known AsTMP; Proloprim; Monotrim
CAS Number738-70-5
Molecular FormulaC₁₄H₁₈N₄O₃
Molecular Weight290.32 g/mol
CategoryAntibacterial / Antiprotozoal Agent
AppearanceWhite to cream crystalline powder
SolubilitySlightly soluble in water; soluble in methanol and dilute acids
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TMP/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
💬
Mediocon AI
Hello 👋 How can I help you today?