Also known as: Pamapimod; 8-bromotheophylline 2-amino-2-methyl-1-propanol salt
Pamabrom is a mild diuretic commonly combined with analgesics (e.g., acetaminophen, ibuprofen) in OTC menstrual relief products to reduce water retention, bloating, and puffiness associated with premenstrual syndrome. It is the 8-bromotheophylline salt of 2-amino-2-methyl-1-propanol. Mediocon Inc manufactures this API at its GMP-certified facility in Aurangabad, Maharashtra, India.
| Parameter | Specification |
|---|---|
| CAS Number | 1311226-67-0 |
| Molecular Formula | C19H19F2N5O2 |
| Molecular Weight | 373.38 g/mol |
| Grade | IP / BP / USP |
| Category | Diuretic / Analgesic Adjuvant |
| Appearance | White to off-white powder |
| Solubility | Freely soluble in DMSO, slightly soluble in water |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PAP/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |