Active Pharmaceutical Ingredient

Pamidronic Acid — CAS 40372-72-3

Also known as: APD; 3-amino-1-hydroxypropylidene-1,1-bisphosphonic acid

GMP Certified IP / BP / USP Bisphosphonate / Bone Resorption Inhibitor Aurangabad, India
Pamidronic Acid API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pamidronic Acid IP / BP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 40372-72-3

Product Overview

Pamidronic Acid (free acid form of pamidronate) is a nitrogen-containing bisphosphonate compound that inhibits osteoclastic bone resorption. It is used as the active moiety in pamidronate disodium formulations. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India.

Therapeutic Applications
  • Precursor / free acid form for pamidronate disodium synthesis
  • Treatment of hypercalcemia of malignancy
  • Research in bone metabolism and osteoclast biology
  • Active component in bisphosphonate drug development

Technical Specifications

ParameterSpecification
CAS Number40372-72-3
Molecular FormulaC10H21N2O7P2
Molecular Weight322.23 g/mol
GradeIP / BP / USP
CategoryBisphosphonate / Bone Resorption Inhibitor
AppearanceWhite to off-white crystalline powder
SolubilityFreely soluble in water, sparingly soluble in ethanol
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPAD/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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