Also known as: APD; 3-amino-1-hydroxypropylidene-1,1-bisphosphonic acid
Pamidronic Acid (free acid form of pamidronate) is a nitrogen-containing bisphosphonate compound that inhibits osteoclastic bone resorption. It is used as the active moiety in pamidronate disodium formulations. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India.
| Parameter | Specification |
|---|---|
| CAS Number | 40372-72-3 |
| Molecular Formula | C10H21N2O7P2 |
| Molecular Weight | 322.23 g/mol |
| Grade | IP / BP / USP |
| Category | Bisphosphonate / Bone Resorption Inhibitor |
| Appearance | White to off-white crystalline powder |
| Solubility | Freely soluble in water, sparingly soluble in ethanol |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PAD/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |