Active Pharmaceutical Ingredient

Pamidronate Disodium — CAS 158749-09-6

Also known as: Aredia (brand); Disodium pamidronate; APD disodium

GMP Certified IP / BP / USP Bisphosphonate / Bone Resorption Inhibitor Aurangabad, India
Pamidronate Disodium API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pamidronate Disodium IP / BP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 158749-09-6

Product Overview

Pamidronate Disodium is a bisphosphonate that inhibits osteoclast-mediated bone resorption. It is used in the treatment of hypercalcemia of malignancy, Paget's disease of bone, and osteolytic lesions of multiple myeloma and breast cancer. Mediocon Inc manufactures this API at its GMP-certified facility in Aurangabad, Maharashtra, India.

Therapeutic Applications
  • Treatment of hypercalcemia of malignancy
  • Management of Paget's disease of bone
  • Prevention and treatment of osteolytic bone lesions in multiple myeloma
  • Treatment of osteolytic metastases from breast carcinoma

Technical Specifications

ParameterSpecification
CAS Number158749-09-6
Molecular FormulaC22H30N2Na2O12P2
Molecular Weight617.43 g/mol
GradeIP / BP / USP
CategoryBisphosphonate / Bone Resorption Inhibitor
AppearanceWhite to off-white crystalline powder
SolubilityFreely soluble in water, slightly soluble in ethanol
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPAD/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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