Also known as: Aredia (brand); Disodium pamidronate; APD disodium
Pamidronate Disodium is a bisphosphonate that inhibits osteoclast-mediated bone resorption. It is used in the treatment of hypercalcemia of malignancy, Paget's disease of bone, and osteolytic lesions of multiple myeloma and breast cancer. Mediocon Inc manufactures this API at its GMP-certified facility in Aurangabad, Maharashtra, India.
| Parameter | Specification |
|---|---|
| CAS Number | 158749-09-6 |
| Molecular Formula | C22H30N2Na2O12P2 |
| Molecular Weight | 617.43 g/mol |
| Grade | IP / BP / USP |
| Category | Bisphosphonate / Bone Resorption Inhibitor |
| Appearance | White to off-white crystalline powder |
| Solubility | Freely soluble in water, slightly soluble in ethanol |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PAD/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |