Also known as: Zemplar (brand); 19-nor-1,25-dihydroxyvitamin D2; 19-nor-vitamin D2
Paricalcitol is a synthetic vitamin D analog used in the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD). It selectively activates the vitamin D receptor (VDR) in the parathyroid glands and reduces PTH levels. Mediocon Inc manufactures this API at its GMP-certified facility in Aurangabad, Maharashtra, India.
| Parameter | Specification |
|---|---|
| CAS Number | 137000-91-6 |
| Molecular Formula | C27H40O3 |
| Molecular Weight | 412.61 g/mol |
| Grade | IP / BP / USP |
| Category | Vitamin D Analog / Secondary Hyperparathyroidism Treatment |
| Appearance | White to off-white, crystalline powder |
| Solubility | Practically insoluble in water, freely soluble in ethanol and in methanol |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PCI/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |